Nọmba Cas: 224785-91-5 Fọọmu Molecular: C23H33ClN6O4S Aworan Ifihan

Nọmba Cas: 224785-91-5 Molecular Formula: C23H33ClN6O4S

Apejuwe kukuru:

Cas nọmba: 224785-91-5

Orukọ Kemikali:

Fọọmu Molecular:C23H33ClN6O4S

Awọn itumọ ọrọ: HCL;Vardenafi;Nuviva;fafinafei;Valdenafil;Levitra,Valdenafil;USP/EP/BP;Lefitira,Valdenafil.HCl;224785-91-5;

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Alaye ọja

ọja Tags

Awọn ọja Specification

Ojuami Iyo	214-216°C
iwuwo	N/A
iwọn otutu ipamọ	Afẹfẹ inert, 2-8°C
solubility	N/A
opitika aṣayan iṣẹ-ṣiṣe	N/A
Ifarahan	Funfun to Pa-White Cyrstalline
Mimo	≥98%

pharmacodynamics

jẹ aṣoju keji lati wa ni tita ati pe o ni anfani pe akoko ibẹrẹ rẹ ko dinku nipa gbigbe oogun naa ni ikun ni kikun.O jẹ awọn akoko 30 diẹ sii ni agbara bi onidalẹkun ti PDE5 (tumọ si IC50, 3.9 nM) ju sildenafil ati awọn akoko 10 diẹ sii ju tadalafil lọ, pẹlu yiyan ti o tobi ju (> awọn akoko 1,000) fun eniyan PDE5 ju fun eniyan PDE2, PDE3, ati PDE4 ati yiyan yiyan (> 80 igba) fun PDE1.Aṣayan inhibitory PDE ati mejeeji in vitro ati agbara in vivo ti inhibitor PDE5 tuntun.pataki ni idinamọ hydrolysis ti cGMP nipasẹ PDE5, pẹlu IC50 ti 0.7 nM (sildenafil 6.6 nM).IC50 ti fun PDE1 jẹ 180 nM, fun PDE6 11 nM, ati fun PDE2, PDE3 ati PDE4 diẹ sii ju 1,000 nM.