Nọmba Cas Florfenicol: 73231-34-2 Fọọmu Molecular: C12H14Cl2FNO4S
2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamide
AQUAFEN FLORFENICOL NUFLOR
[r- (r*, r*)] -n-[1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulforyl) phenyl) -ethyl] -2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]ACETAMIDE
SCH-25298
(r- (r*,s*)) -methyleste
2,2-dichloro-n- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) phenyl) ethyl
4- (2- ((dichloroacetyl) amino) -3-fluoro-1-hydroxypropyl) -benzenesulfonicaci
Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N- (1S,2R) -1- (fluoromethyl) -2-hydroxy-2-4- (methylsulfonyl) phenylethyl-
2,2-Dichloro-N-[(1S,2R) -1- (fluoromethyl) -2-hydroxy-2- [4- (methylsulfonyl) phenyl] ethyl] acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R- (R*, S*)] -2,2-Dichloro-N-[1- (fluoromethyl) -2-hydroxy-2- [4- (methylsulfonyl) phenyl] ethyl ] acetamide
2,2-Dichloro-N- (1- (fluoromethyl) -2-hydroxy-2- (4- (methylsulfonyl) phenyl) ethyl) acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1- (4-methylsulfonylphenyl) propan-2-yl] acetamid
| Ojuami Iyo | 153 ° |
| iwuwo | 1.451± 0.06 g/cm3 (Asọtẹlẹ) 1.1782 (iṣiro ti o ni inira) |
| iwọn otutu ipamọ | 2-8°C |
| solubility | Soluble ni ethanol si 25mM ati ni DMSO si 100mM |
| opitika aṣayan iṣẹ-ṣiṣe | N/A |
| Ifarahan | Funfun to Pa-White |
| Mimo | ≥98% |
Florfenicol jẹ oogun apakokoro fluorinated ti o gbooro ati itọsẹ ti thiamphenicol (Nkan Nkan. 21357).O n ṣiṣẹ lọwọ lodi si awọn iyasọtọ ile-iwosan eniyan ti awọn kokoro arun inu, pẹlu E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, ati Salmonella (MIC)50s = 6.3-12.5 μg/ml).Florfenicol tun n ṣiṣẹ lọwọ lodi si awọn iyasọtọ ile-iwosan ti awọn oriṣiriṣi bovine ati porcine ti atẹgun atẹgun, pẹlu P. multocida, A. pleuropneumoniae, ati B. bronchiseptica (MIC)50s = 0.25-4 μg/ml).O ṣe idiwọ iṣẹ-ṣiṣe gbigbe peptidyl ni 70S ribosomes ti o ya sọtọ lati E. coli nigba lilo ni ifọkansi ti 1 mM.Awọn agbekalẹ ti o ni florfenicol ni a ti lo ni itọju ti arun atẹgun ti o ni akoran ninu awọn malu.
O jẹ iru oogun antibacterial kan.O ti wa ni lo bi awọn ti ogbo antimicrobial oloro fun atọju kokoro arun ti elede, adie ati eja.O ni ipa ti o dara ni ṣiṣe itọju arun ikolu ti awọn ẹlẹdẹ, awọn adie ati ẹja ti o fa nipasẹ awọn kokoro arun ti o ni itara, paapaa fun atọju awọn akoran atẹgun ati awọn akoran inu.
